Geng Chen

Fish Genetics and Genomics

Yangtze River Fisheries Research Institute
Chinese Academy of Fishery Sciences, Wuhan, China

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About

I study the genetic basis of economically important traits in freshwater fish, particularly bighead carp (Hypophthalmichthys nobilis) and European perch (Perca fluviatilis). My research combines whole-genome resequencing, population genomics, genome-wide association studies, QTL mapping, and transcriptomics to investigate growth, body shape, sex determination, and environmental adaptation.

My work aims to identify genetic variants and candidate genes that can support genetic improvement and molecular breeding in freshwater aquaculture.

Research Interests

• Quantitative genetics and trait mapping: genetic architecture of growth and body shape; heritability estimation, GWAS, and QTL mapping.
• Fish genomics and population genetics: genome assembly, genetic variation, population structure, and genomic relatedness.
• Sex determination: sex-associated genomic regions and molecular markers.
• Environmental adaptation: physiological and transcriptomic responses to temperature, alkalinity, and other environmental challenges.

Selected Publications

Genetic Architecture and Molecular Breeding

1. Chen G, Peng F, Wang D, Tong J, Xu J. (2026). Whole-Genome Resequencing Identifies Loci Associated with Body Weight and Body-Size-Related Head Height in Bighead Carp (Hypophthalmichthys nobilis). Biology, 15(20), 1896.
   Article

2. Chen G, Peng F, Wang D, Xu J. (2026). Family-Aware Genome-Wide Association Mapping of Growth and Body-Shape Traits in Bighead Carp (Hypophthalmichthys nobilis). Animals, 16(20), 3271.
   Article

3. Chen G, Liu H, Yu X, Luo W, Tong J. (2023). Estimation of heritabilities and quantitative trait loci for growth traits of bighead carp (Hypophthalmichthys nobilis). Aquaculture, 566, 739213.
   DOI

4. Chen G, Zhou Y, Yu X, Wang J, Luo W, Pang M, Tong J. (2022). Genome-Wide Association Study Reveals SNPs and Candidate Genes Related to Growth and Body Shape in Bighead Carp (Hypophthalmichthys nobilis). Marine Biotechnology, 24, 1138–1147.
   DOI

5. Zhou Y, Fu B, Yu X, Chen G, Wang J, Luo W, Feng Y, Tong J. (2021). Genome-wide association study reveals genomic regions and candidate genes for head size and shape in bighead carp (Hypophthalmichthys nobilis). Aquaculture, 539, 736648.
   DOI

Environmental Adaptation in European Perch

1. Chen G, Peng F, Chen P, Xu J. (2026). Integrated Physiological and Transcriptomic Analyses Suggest Key Adaptive Mechanisms of European Perch (Perca fluviatilis) to Acute Heat Stress. Animals, 16(13), 2007.
   Article

2. Chen G, Liu Y, Li X, Gao P, Hu J, Sun P, Peng F, Chen P, Xu J. (2025). Transcriptomic and Physiological Responses Reveal a Time-Associated Multi-Organ Injury Pattern in European Perch (Perca fluviatilis) Under Acute Alkaline Stress. Animals, 15(24), 3621.
   Article

Functional Genomics and Host–Pathogen Interactions

1. Chen G, et al. (2018). ITGB1b-Deficient Rare Minnows Delay Grass Carp Reovirus (GCRV) Entry and Attenuate GCRV-Triggered Apoptosis. International Journal of Molecular Sciences, 19(10), 3175.
   Article

View the full publication list on Google Scholar

Research Funding

National Natural Science Foundation of China (NSFC)
Young Scientists Fund · Grant No. 32302990 · Principal Investigator

Contact

Email: chengeng@yfi.ac.cn
Affiliation: Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences
Location: Wuhan, China

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Last updated: October 2026